Pharmaceutical Care Network Europe

The Pharmaceutical Care Network Europe (PCNE) was established in 1994 by a number of European pharmaceutical care researchers. It became an official association (under Dutch law) in 2004.

Medication Review Drug-related problem classification Guidelines and Indicators

Looking for the different versions of the PCNE-DRP classification? Look at the bottom of this page.

15-2-2019: Classification V 8.03

Version 8.03 is ready and available, incorporating some validation results of V7.0, and correcting some minor issues in V8.0, V 8.01 and V8.02.
Please note that Version V 8 is not compatible with earlier versions, due to some fundamental changes. The version 8.03 is being validated by an international group of experts . This version is also available in Mandarin Chinese, Traditional Chinese and Turkish (see below).

PCNE Working group on drug-related problems.

Drug-related problems are one of the cornerstones of pharmaceutical care. Therefore the working group on Drug-related problems develops and evaluates a DRP-classification.

In September 2009 the working group on Drug-related problems of the Pharmaceutical Care Network Europe has been officially estabished, although it existed already informally since 2001. The working group is currently chaired by Dr. Nina Griese and Dr. Tommy Westerlund and Dr. Nejc Horvat. PCNE also defined a Drug-related propblem, on which the classification is also based:

"A Drug-Related Problem is an event or circumstance involving drug therapy that actually or potentially interferes with desired health outcomes."


Short history of the PCNE DRP-classification

During the first Working Conference of the Pharmaceutical Care Network Europe in January 1999 in Hilleroed, Denmark, a classification scheme was constructed for drug related problems (DRPs). In the years thereafter the classification underwent many tests and changes, leading to a number of new versions.

The definition of drug-related problems, and the 2009 version of the PCNE-DRP classification have been extensively discussed during a dedicated and important PCNE Working Symposium on Drug Related Problems in Geneva. There were international 18 experts present who discussed definitions, the new version (V6) of the PCNE DRP classification and validation issues.

The different abstracts, presentations and reports from that meeting are available from Working Symposium 2009.

In 2017, a new discussion round was held between experts, and this was the start for the creation of a new version . One of the essential new elements was a domain for the way that the proposed interventions are presented, and one for the level acceptance of the intervention. The domain outcome was also scrutenised and adapted.

After a quick validation and a new discussion on the validation process in Heidelberg, some minor changes were implemented and V8 became the new standard. During the 2019 Working Conference in Egmond, the Classification and its validation were again discussed, and this lead to some minor changes. The current version is V8.03.

In due course a new domain will be added on possible causes that can be found in seamless care (patient transfer between different settings or clinical departments).

Additional information can be obtained from the professional secretariat of the PCNE.

The PCNE DRP-classification

Looking for the most recent version of the PCNE-DRP classification? Click Here or look at the end of this page.

Please note that per 20-2-2019, the latest version is V8.03. Previous versions are no longer supported, but some can still be downloaded.

The versions 8 are not compatible with earlier versions, due to some fundamental changes. But V8.03 is compatible with V8.0, V8.01 and V8.02. The English edition of this version will be validated. There is a Mandarin translation and Traditional Chinese translation, and a Turkish translation of Version 8.03. Versions in Russian, Ukrainian and German are under scruteny.

There is a Spanish and Croatian version version of the Classification V6.2. These versions are no longer supported by PCNE but have proven their worth in several projects.

Please note that there is a copyright on the material, and you should inform the PCNE secretariat if you want to use or publish the Classification or related materials (any version).

The classification has changed significantly since its first version. A list of the changes can be found here.

Links to the classification

If you want to contribute to the validation or translation of the DRP Classification V8.03, please contact the PCNE secretariat at The secretariat also has a .sav file available for entering data for evaluating the results of the classification in SPSS.

Older versions: